Product Overview
Composition
Bioactive extract from small sea fish - 1.0 ml
pharmachologic effect
AMBENE® Bio is a chondroprotector, the active ingredient of which is a bioactive extract from small sea fish.
The extract contains mucopolysaccharides (chondroitin sulfate), amino acids, peptides, sodium, potassium, calcium, magnesium, iron, copper and zinc ions.
AMBENE® Bio prevents the destruction of macromolecular structures of normal tissues, stimulates recovery processes in the interstitial tissue and tissue of the articular cartilage, which explains its analgesic effect.
The anti-inflammatory effect and tissue regeneration are based on the inhibition of the activity of hyaluronidase and the normalization of the biosynthesis of hyaluronic acid. Both of these effects are synergistic and cause the activation of regenerative processes in tissues (in particular, the restoration of the cartilage structure).
Indications
AMBENE ® Bio is used in adults with primary and secondary osteoarthritis of various localization (coxarthrosis, gonarthrosis, arthrosis of small joints), osteochondrosis and spondylosis.
Contraindications
Hypersensitivity to drug components.
Pregnancy and lactation.
Side effects
The frequency of the adverse reactions listed below was determined according to the following gradation: very often (> 1/10), often (> 1/100, ≤1 / 10), infrequently (> 1/1000, ≤1 / 100), rarely (> 1/10000, ≤1 / 1000), very rare (≤1 / 10000).
Allergic reactions: rarely - itching; very rarely - anaphylactic reactions.
Local: rarely - skin redness and burning sensation at the injection site.
Interaction
So far not identified.
How to take, course of administration and dosage
For polyosteoarthritis and osteochondrosis, the drug is administered deeply intramuscularly, 1 ml per day. The course of treatment is 20 injections (1 injection per day for 20 days).
With a predominant lesion of large joints, the drug is injected intra-articularly in 1-2 ml into each joint with an interval of 3-4 days. A total of 5-6 injections in each joint for a course.
A combination of intra-articular and intramuscular administration is possible.
Overdose
In case of an overdose in predisposed patients, allergic reactions (sometimes severe) may occur.
Special instructions
In case of individual intolerance to seafood (sea fish), the risk of developing allergic reactions increases.
Release form
Injection.
1.0 ml in ampoules of light-protective (SNS-1) or brown (NB) imported glass.
5 ampoules are placed in a blister strip made of polyvinyl chloride film.
2 blister packs together with instructions for use are placed in a carton box. An ampoule knife or scarifier is put into the pack.
Storage conditions
In a dark place at a temperature of 15-25 ° C.
Keep out of the reach of children.
Shelf life
2 years. Do not use after the expiration date printed on the package.
