Product Overview
Structure
1 tablet contains:
salbutamol - 2 mg,
Bromhexine - 8 mg,
guaifenesin - 100 mg.
pharmachologic effect
Ascoril is a combined drug with bronchodilator and expectorant action.
Salbutamol is a selective agonist of β2-adrenergic receptors, has a bronchodilator effect, relieves bronchospasm.
Bromhexine has a mucolytic effect. Reduces the viscosity of bronchial secretions due to depolarization of acidic polysaccharides and stimulation of secretory cells of the mucous membranes of the bronchi.
Guaifenesin reduces the surface tension and adhesive properties of sputum, contributes to its expectoration.
Indications
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Bronchial asthma;
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acute and chronic bronchitis;
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bronchiectasis;
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atelectasis;
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emphysema;
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pneumonia;
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whooping cough;
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pulmonary tuberculosis;
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other bronchospastic conditions.
Contraindications
Tachycardia; heart rhythm disturbances; hypersensitivity to the components of the drug.
Side effects
Rarely: hand tremor, tachycardia, muscle cramps.
When used in high doses - tachycardia, headache, peripheral vasodilation.
Interaction
Other beta2-adrenergic agonists and theophylline enhance the effects of salbutamol and increase the likelihood of side effects.
Ascoril is not prescribed simultaneously with preparations containing codeine and other antitussive drugs, as this makes it difficult to discharge liquefied sputum.
Ascoril bromhexine, which is part of the drug, promotes the penetration of antibiotics (erythromycin, cephalexin, oxytetracycline) into the lung tissue.
It is not recommended to use the drug Ascoril simultaneously with non-selective beta-adrenergic receptor blockers, such as propranolol.
Ascoril salbutamol, which is part of the drug, is not recommended for patients who receive MAO inhibitors.
Diuretics and corticosteroids enhance the hypokalemic effect of salbutamol.
It is not recommended to take alkaline drink at the same time as Ascoril.
How to take, course of administration and dosage
The drug Ascoril is taken orally.
The dosage for adults and children over 12 years is 1 tablet 3 times a day.
For children aged 6 to 12 years, Ascoril is prescribed 1/2 tablet 3 times a day.
Overdose
Symptoms: increased manifestations of side effects.
Treatment: symptomatic therapy.
Special instructions
With caution, the drug is prescribed for patients with hyperthyroidism, diabetes mellitus, severe diseases of the cardiovascular system, arterial hypertension, peptic ulcer of the stomach and duodenum.
Release form
Tablets.
