Product Overview
Composition
1 ml of the drug (1 ampoule) contains:
Sodium adenosine triphosphate disubstituted (in terms of adenosine triphosphate) - 10 mg,
Excipients.
pharmachologic effect
An agent that improves metabolism and energy supply to tissues. ATP is a natural component of body tissues - it is involved in many metabolic processes.
When ATP breaks down into ADP and inorganic phosphate, energy is released, which is necessary for muscle contraction and various biochemical processes.
ATP is involved in the transmission of excitation in adrenergic and cholinergic synapses, facilitates the transmission of excitation from the vagus nerve to the heart.
Apparently, ATP is one of the mediators that excite adenosine receptors. Strengthens cerebral and coronary blood circulation, increases peripheral blood circulation.
Triphosadenine is an adenosine derivative.
Adenosine is an agonist of purinergic receptors, the activation of which leads to inhibition of depolarization of the processes of conducting electrical impulses in the sinus and AV nodes.
This effect underlies the antiarrhythmic action of triphosadenine in supraventricular tachycardia.
Acts for a short time within a few seconds.
Indications
Muscular dystrophy, myoatrophy, obliterating atherosclerosis of the vessels of the lower extremities, Raynaud's disease, thromboangiitis obliterans, paroxysmal supraventricular tachycardia.
Recommendations for use
In / m - 1 ml of 1% solution 1-2 times a day.
The course of treatment is 30-40 injections.
A second course - in 1-2 months.
To stop the paroxysm of supraventricular tachycardia, 1-2 ml of 1% solution is injected intravenously (the effect occurs after 30-40 seconds).
Re-introduction - in 2-3 minutes.
Contraindications
Increased individual sensitivity to drug components.
The drug is not prescribed for patients with acute myocardial infarction.
The drug is not used for the treatment of children under the age of 18 due to the lack of reliable data on the safety and efficacy of the drug in this age category.
Side effects
With i / m administration: possible headache, tachycardia, increased urine output, hyperuricemia.
With the on / in the introduction: possible nausea, flushing of the skin of the face, headache, weakness.
Allergic reactions: rarely - itching, flushing of the skin.
Overdose
At the moment, there have been no reports of drug overdose.
Storage conditions
It is recommended to store the drug in a dry place away from direct sunlight at a temperature of 3 to 5 ° C.
Shelf life
1.5 years
