Clenbuterol

Sopharma, Bulgaria

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$17 - $19
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Product Overview

Structure

Active substance:

Clenbuterol hydrochloride - 5 mcg.

Excipients :

 lactose monohydrate - 70 mg;

wheat starch - 31.48 mg;

MCC - 48.5 mg;

colloidal silicon dioxide - 2 mg;

magnesium stearate - 2 mg;

povidone (povidone K25) - 6 mg

pharmachologic effect

Clenbuterol is a selective β2-adrenergic agonist.
 
It has a bronchodilator and secretolytic effect. It stimulates β2-adrenergic receptors, stimulates adenylate cyclase, increases the content of cAMP in the cells, which, affecting the protein kinase system, deprives myosin of the ability to bind to actin and helps to relax the bronchi. It inhibits the release of mediators from mast cells that contribute to bronchospasm and inflammation of the bronchi.
 
Reduces edema or congestion in the bronchi, improves mucociliary clearance.

Indications

Bronchial asthma, chronic obstructive pulmonary disease.

Contraindications

Contraindicated in pregnancy and lactation.

Side effects

From the cardiovascular system: tachycardia, extrasystole, arterial hypo- or (more often) hypertension, cardialgia, facial flushing.

From the side of the central nervous system and peripheral nervous system: finger tremors, anxiety, headache, dizziness, general weakness, insomnia, paresthesia.

From the digestive system: dry mouth, nausea, vomiting, gastralgia.

Allergic reactions: skin rash, urticaria, bronchospasm, angioedema.

Other: increased sweating, hypokalemia, muscle cramps. With a sharp withdrawal of the drug, the development of resistance and rebound syndrome is possible. When used in large doses, causes tremor of the fingers.

How to take, course of administration and dosage

It is applied inside.

Adults and children over 12 years old - 10–20 mcg 2-3 times a day, maintenance dose - 10 mcg 2 times a day.

Young children - in reduced doses, depending on age, 2 times a day.

Overdose

Symptoms: arrhythmia, tachycardia, arterial hypertension, cardialgia, tremor of the extremities, the development of hypokalemia is possible.

Treatment: gastric lavage, the appointment of activated carbon, the use of water-salt solutions, monitoring the level of potassium in the blood serum, symptomatic therapy.

Storage conditions

List B.
 
The drug should be stored in a dark place, out of reach of children at a temperature not exceeding 25 °, do not freeze.

Shelf life

3 years.

Do not use after the expiration date indicated on the package.

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