Derinat

1 ml of the solution contains sodium deoxyribonucleate - 2.5 mg,

sodium chloride - 1.0 mg

The drug activates cellular and humoral immunity. Optimizes specific reactions against fungal, viral and bacterial infections. The drug stimulates reparative and regenerative processes, normalizes the state of tissues and organs with dystrophy of vascular origin.

Derinat promotes the healing of trophic ulcers of various etiologies. Derinat promotes the rapid healing of deep burns, significantly accelerating the dynamics of epithelization. With the restoration of ulcerative formations on the mucosa under the action of Derinat, scarless recovery occurs. The drug does not have teratogenic and carcinogenic effects.

Pharmacokinetics:

When applied topically, derinat is rapidly absorbed and distributed in organs and tissues with the participation of the endolymphatic transport pathway. In the phase of intensive drug intake into the blood, a redistribution occurs between plasma and blood cells, in parallel with metabolism and excretion. Derinat is metabolized in the body.

It is excreted from the body (in the form of metabolites) partially with feces, and, to a greater extent, with urine according to biexponential dependence.

Monotherapy:

• acute respiratory infections (ARI);
• prevention and treatment of acute respiratory viral infections (ARVI);
• ophthalmology: inflammatory and dystrophic processes;
• inflammatory diseases of the mucous membranes of the oral cavity;

Complex therapy:

• chronic inflammatory diseases, fungal, bacterial and other infections of the mucous membranes in gynecology;
• acute and chronic diseases of the upper respiratory tract (rhinitis, sinusitis, sinusitis, frontal sinusitis);
• obliterating diseases of the lower extremities;
• trophic ulcers, long-term non-healing and infected wounds (including diabetes mellitus);
• gangrene;
• burns, frostbite;
• hemorrhoids;
• post-radiation necrosis of the skin and mucous membranes.

• hypersensitivity to the components of the drug.

With external and local use of the drug, no side effects were detected.

Derinat in the form of a solution for external and local use is prescribed depending on the localization of the pathological process. The drug is prescribed for children from the first day of life and adults. For the prevention of acute respiratory viral infections, 2 drops are instilled into each nasal passage 2-4 times a day for 1-2 weeks.

When symptoms of a respiratory disease appear, the drug is instilled 2-3 drops in each nasal passage every 1-1.5 hours during the first day, then 2-3 drops in each nasal passage 3-4 Duration of the course of therapy - from 5 days to 1 month . In case of inflammatory diseases of the nasal cavity and sinuses, the drug is instilled 3-5 drops in each nasal passage 4-6 times a day; course duration - 7-15 days. In inflammatory diseases of the oral cavity, rinse the oral cavity with a solution of the drug 4-6 times a day (1 bottle for 2-3 rinses). The duration of the course of therapy is 5-10 days.  

In chronic inflammatory diseases, fungal, bacterial and other infections in gynecological practice - intravaginal administration of tampons with the drug or irrigation of the vagina and cervix of 5 ml per procedure 1-2 times a day for 10-14 days. With hemorrhoids, the drug is administered rectally with a microclyster of 15-40 ml.

The duration of treatment is 4-10 days. In ophthalmic practice in severe inflammatory and dystrophic processes, Derinat is instilled in the eyes 1-2 drops 2-3 times a day for 14-45 days. With obliterating diseases of the lower extremities, in order to achieve a systemic effect, the drug is instilled 1-2 drops in each nasal passage 6 times a day, the duration of the course is up to 6 months. 

In case of post-radiation necrosis of the skin and mucous membranes, with long-term non-healing wounds, burns, frostbite, trophic ulcers of various etiologies, gangrene, it is recommended to apply dressings (gauze in 2 layers) with the preparation 3-4 times a day or treat the affected surface preparation from a spray of 10-40 ml 4-5 times a day. The course of treatment is 1-3 months.

Spray.