Fenibut

Olainpharm, Latvia

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$12 - $46
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Product Overview

Contents

Each tablet contains:
Active ingredient: Aminophenylbutyric acid hydrochloride - 250 mg (phenibut)
Auxiliary substances:
lactose monohydrate - 180 mg
pregelatinized corn starch - 57.7 mg
Searic acid - 5 mg

Pharmacological action

Aminophenylbutyric acid (AFC) normalizes metabolic processes in the nerve cells of the brain. The active ingredient can be considered as a derivative of gamma-aminobutyric acid or as a derivative of beta-phenylethylamine. Aminophenylbutyric acid has nootropic activity, and as a derivative of GABA has anti-anxiolytic activity. Does not affect choline and adrenergic receptors.
The active ingredient reduces tension, anxiety, fear and improves sleep, so it is used to treat neuroses and before surgery. AFC lengthens and enhances the effect of sleeping pills, narcotic, neuroleptic and antiparkinsonian drugs.
AFC is deprived of anticonvulsant activity. The active substance lengthens the latent period of nystagmus and shortens its duration and severity. The active ingredient also reduces the manifestations of asthenia and vasovegetative symptoms, including headache, feeling of heaviness in the head, sleep disorders, irritability, emotional lability and increases mental performance. Psychological indicators (attention, memory, speed and accuracy of sensorimotor reactions) under the influence of AFC improve, in contrast to the influence of tranquilizers. Patients with asthenia and emotionally labile patients from the first days of therapy improve their subjective well-being, interest and initiative, motivation for activity.

Indications

asthenic and anxiety-neurotic conditions;
stuttering, tics, enuresis in children;
insomnia and night anxiety in the elderly;
Meniere's disease, dizziness associated with dysfunction of the vestibular analyzer of various genesis;
prevention of motion sickness in kinetosis;
as part of complex therapy for alcohol withdrawal syndrome to relieve psychopathological and somatovegetative disorders.

Contraindications

Hypersensitivity to the active ingredient or excipients of the drug, acute renal failure, pregnancy, breastfeeding, children under 3 years of age.

Side effects

Frequency unknown - hypersensitivity reactions (including urticaria, itching, erythema, rashes, angioedema, facial swelling, tongue swelling)
The frequency is unknown - drowsiness (at the beginning of treatment), dizziness, headache (when taken at a dose of more than 2 g per day, when the dose is reduced, the severity of the side effect decreases)
Frequency unknown - nausea (at the beginning of treatment)
Rarely - allergic reactions (skin itching, rash)
Frequency unknown - with long-term use of high doses - hepatotoxicity

Interaction

When used together, Phenibut lengthens and enhances the effect of sleeping pills, neuroleptics, anticonvulsants.

How to take, course and dosage

Inside after a meal, with enough water. The pills can be divided.
Asthenic and anxiety-neurotic conditions:
Adults: 250-500 mg 3 times a day. The maximum single dose is 750 mg (3 tablets), for patients over 60 years of age - 500 mg. The course of treatment is 2-3 weeks. If necessary, the course of treatment can be extended to 4-6 weeks.
Children: 3-8 years old - 125 mg up to once a day; 8-14 years old - 250 mg 3 times a day; children over 14 years old - doses for adults

Stuttering, tics and enuresis in children: 3-8 years - 125 mg up to once a day; 8-14 years - 250 mg 3 times a day; children over 14 years - doses for adults

Insomnia and night anxiety in the elderly: 250-500 mg 3 times a day

Meniere's disease, dizziness associated with dysfunction of the vestibular analyzer: During the period of exacerbation in adults - 750 mg 3-4 times a day for 5-7 days, then 250-500 mg 3 times a day for 5-7 days and then 250 mg once a day for 5 days. For the treatment of dizziness in dysfunctions of the vestibular analyzer of vascular and traumatic genesis - 250 mg 3 times a day for 12 days.

Prevention of motion sickness in kinetosis: 250-500 mg once 1 hour before the intended journey or when the first symptoms of motion sickness appear.

In case of alcoholic withdrawal syndrome: at the beginning of treatment during the day, 250-500 mg once a day and at night 750 mg, with a gradual decrease in the dose to the usual for adults.

Overdose

The drug is low-toxic. There were no data on cases of overdose. Symptoms: drowsiness, nausea, vomiting, dizziness. Long-term use of high doses may develop eosinophilia, lower blood pressure, impaired kidney function, fatty liver dystrophy (intaken more than 7 g).
Treatment: gastric lavage, symptomatic treatment, maintenance of vital functions. There is no specific antidote.

Overview

Phenibut® normalizes metabolic processes in brain nerve cells. The drug reduces tension, anxiety, fear and improves sleep, so it is used to treat neuroses and before surgeries. The drug reduces the manifestations of asthenia and vasovegetative symptoms, including headache, feeling of heaviness in the head, sleep disorders, irritability, emotional lability and increases mental performance. Psychological indicators under the influence of Fenibut® improve, unlike the influence of tranquilizers.

Storage conditions

In a dry, dark place, at a temperature not exceeding 25 °C

Expiration date

3 years

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