Hepa-Merz (Ornitin) 5 g powder for solution

Merz Pharma GmbH and Co.KGAA, Germany

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$27 - $71
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Product Overview

Structure

5g of granules contain:
 
Active substance:
 
L-Ornithine-L-Aspartate 3G
 
Excipients:
 
anhydrous citric acid 0.55 g,
 
lemon flavor 0.02 g,
 
orange flavor 0.2 g,
 
sodium saccharin (sodium saccharin) 0.0045 g,
 
sodium cyclomat 0.0405 g,
 
dye sunny sunset yellow 0.0005 g,
 
polyvinylpyrrolidone (povidone) 0.05 g,
 
fructose (levulose) 1.1345 g.

pharmachologic effect

Hepa-Merz - hepatoprotective.

Pharmacodynamics

Participates in the ornithine urea cycle of Krebs (urea biosynthesis from ammonia). Promotes the production of insulin and STH. Improves detoxification function of the liver, lowers elevated plasma ammonia levels. Improves protein metabolism in diseases requiring parenteral nutrition.

Pharmacokinetics

Dissociates into ornithine and aspartate, which are absorbed in the small intestine by active transport through the intestinal epithelium. It is excreted in the urine through a urea cycle.

Indications

Acute and chronic liver diseases accompanied by hyperammonemia. Hepatic encephalopathy (latent and severe). Steatoses and steatohepatitis (of various origins).

Contraindications

Severe renal impairment (plasma creatinine level 3 mg / 100 ml).

Side effects

Rarely - skin reactions, in some cases - nausea, vomiting.

How to take, course of administration and dosage

Inside, after eating, 1 sachet of granulate, previously dissolved in 200 ml of liquid, 2-3 times a day.

Release form

Granules for oral solution

Storage conditions

At a temperature not exceeding 25 ° C.

Shelf life

3 years

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