Iodomarin 0.2 mg, 100 pcs

1 tablet contains:

Active substances: 

potassium iodide 262 mcg, which corresponds to an iodine content of 200 mg.

Excipients: 

lactose monohydrate - 150.238 mg,

magnesium carbonate basic - 56.5 mg,

gelatin - 8 mg 

sodium carboxymethyl starch (type A) - 9.5 mg, 

colloidal silicon dioxide - 3.5 mg, 

magnesium stearate - 2 mg.

Pharmacodynamics

An iodine preparation for the treatment and prevention of thyroid diseases. Iodine is a vital trace element necessary for the normal functioning of the thyroid gland. Thyroid hormones perform many vital functions, including regulate the metabolism of proteins, fats, carbohydrates and energy in the body, the activity of the brain, nervous and cardiovascular systems, genital and mammary glands, as well as the growth and development of the child.

The use of the drug Iodomarin® compensates for the iodine deficiency in the body, preventing the development of iodine deficiency diseases, helps to normalize the thyroid function, which is especially important for children and adolescents, as well as during pregnancy and lactation.

Pharmacokinetics

Data on the pharmacokinetics of the drug Iodomarin® not provided.

• Prevention of endemic goiter (especially in children, adolescents, women during pregnancy and during breastfeeding);
• prevention of relapse of goiter after surgical removal or after the end of drug treatment with thyroid hormone preparations;
• treatment of diffuse euthyroid goiter caused by iodine deficiency in children, adolescents and adults under the age of 40 years.

During pregnancy and lactation, the need for iodine increases, so it is especially important to use the drug Iodomarin® in sufficient doses (200 μg / day) to ensure adequate intake of iodine in the body.

The use of the drug Iodomarin® during pregnancy and during lactation (breastfeeding) is possible only in recommended doses, because the active substance crosses the placenta and is excreted in breast milk.

• Hypersensitivity to iodine;
• hyperthyroidism;
• toxic thyroid adenoma, nodular goiter when used in doses of more than 300 mcg / day (with the exception of the period of preoperative iodotherapy with the aim of blocking the thyroid function);
• herpetiform (senile) dermatitis of Dühring.

The drug should not be used for hypothyroidism, except in cases where the development of the latter is caused by severe iodine deficiency.

Avoid prescribing the drug during therapy with radioactive iodine, the presence or suspected cancer of the thyroid gland.

With the prophylactic use of the drug Iodomarin® in patients of any age, side effects, as a rule, are not observed.

From the endocrine system: when using the drug at a dose of more than 150 μg iodine / day, latent hyperthyroidism can go into a manifest form; when using the drug in a dose exceeding 300 μg iodine / day, iodine-induced thyrotoxicosis may develop (especially in elderly patients suffering from goiter for a long time, in the presence of nodular goiter or diffuse toxic goiter).

Allergic reactions: rarely - iodism, manifested by a metallic taste in the mouth, swelling and inflammation of the mucous membranes (“iodine” rhinitis, conjunctivitis, bronchitis), “iodine” fever, “iodine” acne; in some cases, Quincke's edema, exfoliative dermatitis.

Iodine deficiency increases, and an excess of iodine reduces the effectiveness of hyperthyroidism therapy with thyreostatic drugs (before or during the treatment of hyperthyroidism, it is recommended, if possible, to avoid any use of iodine). On the other hand, thyreostatic drugs inhibit the transition of iodine to an organic compound in the thyroid gland and, thus, can cause goiter formation.

Simultaneous treatment with high doses of iodine and preparations of lithium salts can contribute to the occurrence of goiter and hypothyroidism.

High doses of the drug in combination with potassium-sparing diuretics can lead to hyperkalemia.

Prevention of Endemic Goiter

• Newborns and children under the age of 12 years: 1 / 2-1 tab. the drug Iodomarin® 100 or 1/2 tab. the drug Iodomarin® 200 per day (which corresponds to 50-100 μg of iodine).
• Children over 12 years old and adults: 1-2 tab. the drug Iodomarin® 100 or 1 / 2-1 tab. the drug Iodomarin® 200 per day (which corresponds to 100-200 micrograms of iodine).
• During pregnancy and lactation: 2 tab. the drug Iodomarin® 100 or 1 tab. Iodomarin® 200 per day (which corresponds to 200 mcg of iodine).

Goiter relapse prevention

1-2 tab. the drug Iodomarin® 100 or 1 / 2-1 tab. the drug Iodomarin® 200 per day (which corresponds to 100-200 micrograms of iodine).

Euthyroid goiter treatment

• Newborns and children aged 1 year to 18 years: 1-2 tab. the drug Iodomarin® 100 or 1 / 2-1 tab. the drug Iodomarin® 200 per day (which corresponds to 100-200 micrograms of iodine).
• Adults up to 40 years: 3-5 tab. the drug Iodomarin® 100 per day or 11 / 2-21 / 2 tab. the drug Iodomarin® 200 per day (which corresponds to 300-500 mcg of iodine).

The drug is taken after a meal with a sufficient amount of liquid. When used in children, it is recommended to pre-dissolve the drug in milk or juice.

Prophylactic administration is carried out for several years, if indicated, for life.

For the treatment of goiter in newborns, on average, 2-4 weeks is enough; in children, adolescents and adults, it usually takes 6-12 months, prolonged administration is possible.

The duration of treatment is determined by the attending physician.

Symptoms: staining of the mucous membranes in brown, reflex vomiting (in the presence of starch-containing components in the food, the vomit turns blue), abdominal pain and diarrhea (possibly melena). In severe cases, dehydration and shock may develop. In rare cases, esophageal stenosis, the phenomenon of "iodism" were observed.

Treatment: for acute intoxication - drug withdrawal, gastric lavage with a starch solution, protein or 5% sodium thiosulfate solution until all traces of iodine are removed; in chronic intoxication - discontinuation of the drug. Symptomatic therapy for water imbalance, electrolyte balance, anti-shock therapy.

In the treatment of iodine-induced hypothyroidism, drug withdrawal, metabolic normalization with the help of thyroid hormones.

In the treatment of iodine-induced thyrotoxicosis - with mild forms of treatment is not required, in severe forms, thyrostatic therapy is required (the effect of which is always delayed). In severe cases (thyrotoxic crisis), intensive care, plasmapheresis or thyroidectomy is necessary.

Influence on the ability to drive vehicles and other mechanisms requiring increased concentration of attention

Iodomarin® does not affect the ability to drive vehicles or other potentially dangerous activities.

Pills.