Kipferon 200 mg + 500,000 IU, 10 pcs.

Active ingredients:

immunoglobulin complex preparation (CIP) - 0.2 g,

interferon alpha-2b human,

recombinant - 500,000 IU;

Excipients:

special purpose fat "SolPro" confectionery,

for chocolates and sweets - 0.838 g,

solid petroleum paraffin P-2 - 0.085 g,

emulsifier "Solid" (T-2) - 0.085 g,

sodium hydrogen phosphate dodecahydrate - 0.055mg,

sodium dihydrogen phosphate dihydrate - 0.018 mg,

sodium chloride - 0.110mg,

purified water - 0.012 g

Kipferon is a complex dosage form containing human recombinant interferon-α2 and a complex immunoglobulin preparation (CIP). Interferon-α2 is an activator of innate and acquired immunity, has a pronounced antiviral activity, enhances protection against viral, chlamydial, mycoplasma and bacterial infections, has an immunomodulatory effect in the development of immunological reactions, promotes the growth and preservation of normal intestinal and vaginal flora.

The biological activity of interferon-α2 is realized through interaction with the receptor apparatus of immunocompetent and other cells, leading to an increase in the expression of HLA I and HLA II molecules on the surface of all types of cells and regulation of cell cooperation, an increase in the activity of natural killer cells, as well as imparting resistance to intact cells against their cytolytic actions, proliferation of CD8 T cells. Increases the production of gamma interferon by natural killers. The complex immunoglobulin preparation KIP contains specific and non-specific immunoglobulins of classes G, M, A.

The combination of antiviral, anti-Chlamydia, antibacterial and antitoxic antibodies belonging to different classes of immunoglobulins provides agglutination, neutralization and precipitation of etiotropic pathogenic agents. At the site of application, it stabilizes interferon from secretions of mucous membranes, normalizes local immunity due to the intake of IgA and IgM with suppositories (replacement effect), increases the activity of locally formed cytokines

The drug is used in the complex therapy of diseases accompanied by secondary immunodeficiency states:

• acute respiratory diseases, inflammatory diseases of the oropharynx of bacterial and viral etiology in children and adults;
• acute viral (rotavirus) and bacterial (salmonellosis, dysentery, coli-infection) intestinal infections, including those with manifestations of intestinal dysbiosis of various severity in children;
• urogenital chlamydia in women (including pregnant women in the II-III trimesters of pregnancy), including with manifestations of vaginal dysbiosis, vulvovaginitis, uterine cervicitis, cervical erosion.

Individual intolerance to individual components, pregnancy, I trimester, lactation.

Kipferon is used rectally and vaginally. The drug is used in combination with conventional means of pathogenetic therapy of infectious diseases, as well as antibiotics when indicated. The method and dosage regimen, as well as use in complex treatment, is determined by the doctor depending on the diagnosis, severity and severity of the disease.

Acute respiratory diseases, inflammatory diseases of the oropharynx of bacterial and viral etiology: suppositories are administered rectally (mainly after the act of defecation) for children under 1 year old, one suppository per day, for children under 12 years old - 1 suppository twice a day, for adults and children over 12 years old - 1 suppository three times a day. The most effective and appropriate appointment of "Kipferon" in the acute period of the disease (preferably in the first 3 days). The duration of the course of treatment is determined by the etiology, the severity of the disease, the presence of accompanying complications, pathological conditions and is 5-7 days.

Acute viral (rotavirus) and bacterial (salmonellosis, dysentery, coli-infection) intestinal infections, including those with manifestations of intestinal dysbiosis of various severity in children: suppositories are administered rectally (mainly after the act of defecation) to children under 1 year of age, one suppository a day, children under 12 years old - 1 suppository twice a day, adults and children over 12 years old - 1 suppository three times a day. The most effective and appropriate appointment of the drug in the acute period of the disease (preferably in the first 3 days). The duration of the course of treatment is determined by the etiology, the form of the severity of the disease, the presence of concomitant complications, pathological conditions and is 5-7 days.

Urogenital chlamydia in women (including in pregnant women in the II-III trimesters of pregnancy), including with manifestations of vaginal dysbiosis, vulvovaginitis, uterine cervicitis, cervical erosion: suppositories are injected deeply intravaginally (before contact with the posterior vaginal fornix and cervix) 1-2 suppositories, depending on the severity of the disease, twice a day. The course of treatment is on average 10 days; in the presence of erosion of the cervix, the use of the drug is continued until its epithelialization. If indicated, the course of treatment can be repeated in one month. Treatment should be started in the first days after the end of menstruation. Before the introduction, it is recommended to remove mucus from the mucous membranes of the vagina and cervix.

When used in recommended doses, the drug does not affect the behavior or functional indicators of the body, and also does not affect the ability to drive vehicles, mechanisms.

Vaginal and rectal suppositories.