Product Overview
Composition
Active substance:
melatonin 3 mg;
Excipients:
microcrystalline cellulose 82.4 mg,
sodium carboxymethyl starch (sodium starch glycolate) 10.5 mg,
calcium hydrogen phosphate dihydrate 82.4 mg,
mannitol 44 mg
macrogol 6000 (polyethylene glycol 6000) 15 mg,
magnesium stearate 2.7 mg;
Excipients for the shell:
Opadry II [polyvinyl alcohol 2.4 mg, titanium dioxide 1.5 mg, macrogol 1.212 mg, talc 0.888 mg].
pharmachologic effect
It is a synthetic analogue of the hormone of the pineal gland (pineal gland). Normalizes circadian rhythms. It regulates the sleep-wake cycle, daily changes in locomotor activity and body temperature.
It contributes to the normalization of night sleep (speeds up falling asleep, improves sleep quality, reduces the number of night awakenings, improves well-being after morning awakening, does not cause a feeling of lethargy, fatigue and fatigue upon waking, dreams become more vivid and emotionally saturated).
Adapts the body to a quick change of time zones, reduces stress reactions.
It exhibits immunostimulating and pronounced antioxidant properties.
It inhibits the secretion of gonadotropins, to a lesser extent - other hormones of the adenohypophysis - corticotropin, thyrotropin and growth hormone.
Not addictive and addictive.
Indications
As a sleeping pill.
As an adaptogen for the normalization of biological rhythms.
Contraindications
Hypersensitivity, severe renal impairment, autoimmune diseases, leukemia, lymphoma, allergic reactions, lymphogranulomatosis, myeloma, epilepsy, diabetes mellitus, chronic renal failure, pregnancy and the period of breastfeeding.
Side effects
From the immune system: allergic reactions.
From the central nervous system: headache, morning drowsiness.
From the digestive system: nausea, vomiting, diarrhea.
Other: swelling in the first week of admission.
Interaction
Melatonin enhances the effect of drugs that inhibit the central nervous system and beta-blockers.
It is not recommended to take melatonin in conjunction with hormonal drugs.
Melatonin is not compatible with monoamine oxidase inhibitors (MAOs), glucocorticosteroids, and cyclosporine.
How to take, course of administration and dosage
Inside. Adults 1.5-3 mg 30-40 minutes before bedtime once a day.
As an adaptogen when changing time zones : 1 day before the flight and in the next 2-5 days, 3 mg 30-40 minutes before bedtime.
The maximum daily dose is up to 6 mg per day.
Overdose
Symptoms Increased severity of side effects.
Treatment. Gastric lavage, symptomatic therapy.
Special instructions
During the period of use of the drug, it is recommended to avoid exposure to bright light.
It is necessary to inform women who want to become pregnant about the presence of a weak contraceptive effect in the drug.
Impact on the ability to drive vehicles and mechanisms
During the treatment period, it is necessary to refrain from driving vehicles and engaging in potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.
Release form
Film-coated tablets
