Product Overview
Structure
Active substances:
pancreatin with minimal enzymatic activity:
lipase 3500 IU Ph.Eur;
amylases 4200 IU Ph.Eur;
protease 250 PIECES Ph.Eur.
Excipients:
microcrystalline cellulose,
sodium carboxymethyl starch (type A),
silica colloidal
magnesium stearate.
Shell composition:
talc, hypromellose, azorubine varnish (E122), simethicone emulsion 30% (dry weight), polyacrylate dispersion 30% (dry weight), titanium dioxide (E171), macrogol 6000.
pharmachologic effect
The drug compensates for the insufficiency of exocrine pancreatic function.
The pancreatin enzymes lipase, amylase and protease facilitate the digestion of fats, carbohydrates and proteins, which contributes to their more complete absorption in the small intestine.
Indications
- chronic inflammatory and dystrophic diseases of the stomach, intestines, liver, gall bladder. Conditions after resection or irradiation of these organs, accompanied by impaired digestion of poverty, flatulence, diarrhea (as part of combination therapy);
- to improve digestion, write in patients with normal gastrointestinal function in case of errors in nutrition;
- preparation for x-ray and ultrasound examination of the abdominal organs.
Pregnancy and lactation
The safety of pancreatin during pregnancy is not well understood.
Use is possible in cases where the expected benefit to the mother outweighs the potential risk to the fetus.
Contraindications
- acute pancreatitis;
- exacerbation of chronic pancreatitis.
Side effects
Allergic reactions, diarrhea or constipation, nausea, discomfort in the epigastric region.
With prolonged use in high doses, the development of hyperuricosuria, an increase in the level of uric acid in the blood plasma is possible.
In isolated cases, in patients suffering from cystic fibrosis, stricture formation is observed in the ileocecal region after taking high doses.
Interaction
With the simultaneous use of pancreatin with iron preparations, a decrease in the absorption of the latter is possible.
The simultaneous use of antacids containing calcium carbonate and / or magnesium hydroxide can lead to a decrease in the effectiveness of pancreatin.
How to take, course of administration and dosage
The dose is determined individually depending on the degree of digestion.
- Adults : 1-2 tablets. before meals, without chewing and drinking with water. If necessary, an additional 1-4 tab.
- In children : the drug is used as directed by a doctor.
The duration of treatment can vary from a few days (if the digestive process is disturbed due to errors in the diet) to several months or years (if constant replacement therapy is necessary).
