Oflomelide, 30 g

Active ingredients:

ofloxacin 10 mg;

dioxomethyltetrahydropyrimidine (methyluracil) 40 mg;

lidocaine hydrochloride (in the form of monohydrate) 30 mg;

Excipients :

macrogol 1500 (polyethylene oxide 1500, low molecular weight polyethylene glycol 1500),

macrogol 400 (polyethylene oxide 400, low molecular weight polyethylene glycol 400),

propylene glycol,

methyl parahydroxybenzoate (nipagin or methylparaben),

propyl parahydroxybenzoate (nipazole or propylparaben)

Oflomelide has antimicrobial, anti-inflammatory, local anesthetic, regenerating effect.

Ofloxacin is a broad-spectrum antimicrobial agent from the group of fluoroquinolones. It has a bactericidal effect by blocking DNA gyrase in bacterial cells. Highly active against gram-positive microorganisms: Staphylococcus spp. (including Staphylococcus aureus, Staphylococcus epidermidis), Streptococcus spp .; gram-negative microorganisms: Pseudomonas aeruginosa, Acinetobacter spp., Escherichia coli, Klebsiella spp., Proteus spp., Enterobacter spp., Citrobacter spp .; anaerobes: Propionibacterium acnes; intracellular microorganisms: Chlamydia spp. (including Chlamydia trachomatis), Legionella spp., Mycoplasma spp.

Methyluracil is a tissue repair stimulant. Possesses anabolic activity. Accelerates the processes of cell regeneration in wounds, accelerating the growth and granulation maturation of tissue and epithelialization.

Lidocaine has a local anesthetic effect due to the blockade of sodium channels, which prevents the generation of impulses at the endings of sensitive neurons and the conduction of impulses along nerve fibers. When applied externally, it dilates blood vessels, does not have a local irritating effect.

The water-soluble hydrophilic (hyperosmolar) base of the ointment is a mixture of polyethylene oxides (polyethylene glycols) with a molecular weight of 400 and 1500, which provides a dehydrating (moisture-absorbing) effect on tissues, 20 times stronger than the hyperosmotic effect of 10% sodium chloride solution.

Infected purulent wounds of various localization and etiology in the first (purulent-necrotic) phase of the wound process, incl. accompanied by severe pain syndrome:

• infected burns of II-IV degree;
• bedsores;
• trophic ulcers;
• postoperative and post-traumatic wounds and fistulas;
• wounds after opening abscesses, phlegmon, after surgical treatment of abscessing boils, carbuncles, hydradenitis, suppurating atheroma, lipomas.

Oflomelide is contraindicated in children under 18 years of age, pregnant women and during lactation.

• pregnancy;
• lactation period;
• children and adolescents up to 18 years old;
• hypersensitivity to the components of Oflomelide.

Possibly: allergic reactions.

There were no cases of drug interaction that would lead to a decrease in the effectiveness and safety of the drugs used.

Oflomelid is used externally, once a day for 1-2 weeks. The maximum daily dose should not exceed 100 g of the ointment. The duration of treatment depends on the dynamics of cleansing wounds from purulent exudate and the timing of the relief of the inflammatory process.

After standard treatment of wounds and burns, the ointment is applied directly to the wound surface with a thin layer (after which a sterile gauze bandage is applied) or on a gauze bandage, followed by application to the lesion.

Tampons soaked in ointment loosely fill the cavities of purulent wounds after their surgical treatment, and gauze turundas with ointment are injected into the fistulous passages.

In the treatment of infected burns, the drug is used daily or 2-3 times a week, depending on the amount of purulent discharge.

Before use, you must consult a specialist.

Oflomelide ointment for external use