Product Overview
Composition
Composition per 100 g:
active substances:
ofloxacin - 1 g,
dioxomethyltetrahydropyrimidine (methyluracil) - 4 g,
lidocaine hydrochloride monohydrate (in terms of lidocaine hydrochloride) - 3 g;
Excipients:
methyl parahydroxybenzoate (nipagin or methylparaben),
propyl parahydroxybenzoate (nipazole or propylparaben),
propylene glycol,
macrogol-1500 (low molecular weight polyethylene glycol-1500, polyethylene oxide-1500),
macrogol-400 (low molecular weight polyethylene glycol-400, polyethylene oxide-400).
pharmachologic effect
Pharmacotherapeutic group:
antimicrobial combination agent
ATX code [D06BX]
Oflomelid® is a combined preparation with antimicrobial, anti-inflammatory, local anesthetic, regenerating effect. The active substances are ofloxacin, methyluracil and lidocaine.
Ofloxacin is a broad-spectrum antimicrobial agent from the group of fluoroquinolones. It has a bactericidal effect by blocking DNA gyrase in bacterial cells. Active against gram-negative and gram-positive microorganisms.
Methyluracil is a tissue repair stimulant. Possesses anabolic activity.
Accelerates the processes of cell regeneration in wounds, accelerating the growth and granulation maturation of tissue and epithelialization.
Lidocaine has a local anesthetic effect due to blockade of Na + -channels, which prevents the generation of impulses at the endings of sensitive neurons and the conduction of impulses along nerve fibers. When applied externally, it dilates blood vessels, does not have a local irritating effect.
Indications
An antimicrobial agent is prescribed for purulent, infected wound lesions of various etiology and localization in the purulent-necrotic (first) phase of the wound process, including with concomitant pain syndrome:
- trophic ulcers;
- bedsores;
- infected burns of 2-4 degrees;
- wounds after surgical opening of phlegmon and abscesses;
- after surgical treatment of hydradenitis, carbuncles, abscessing boils, festering lipomas and atheroma;
- post-traumatic and postoperative fistulas and wounds.
Contraindications
- Lactation;
- pregnancy;
- individual hypersensitivity;
- age limit - up to 18 years.
Interaction
There were no cases of drug interaction that would lead to a decrease in the effectiveness and safety of the drugs used.
How to take, course of administration and dosage
Outwardly, once a day for 1-2 weeks. After standard treatment of wounds and burns, the ointment is applied directly to the wound surface in a thin layer (after which a sterile gauze bandage is applied) or on a gauze bandage followed by application to the lesion.
Tampons soaked in ointment loosely fill the cavities of purulent wounds after their surgical treatment, and gauze turundas with ointment are injected into the fistulous passages. In the treatment of purulent wounds, the ointment is used once a day, in the treatment of burns - daily or 2-3 times a week, depending on the amount of purulent discharge. The maximum daily dose should not exceed 100 g. The
duration of treatment depends on the dynamics of cleansing wounds from purulent exudate and the timing of the relief of the inflammatory process.
Tampons soaked in ointment loosely fill the cavities of purulent wounds after their surgical treatment, and gauze turundas with ointment are injected into the fistulous passages. In the treatment of purulent wounds, the ointment is used once a day, in the treatment of burns - daily or 2-3 times a week, depending on the amount of purulent discharge. The maximum daily dose should not exceed 100 g. The
duration of treatment depends on the dynamics of cleansing wounds from purulent exudate and the timing of the relief of the inflammatory process.
Storage conditions
In a dark place at a temperature of 15 to 25 ° C.
Shelf life
2 years.
