Product Overview
Structure
Active substance:
microbial cells of E. coli killed by phenol 660 million ± 25%;
Excipients:
emulsifying solid fat;
macrogol glycerol;
hydroxystearate;
phenol (preservative).
pharmachologic effect
Posterisan - regenerating, antipruritic, immunostimulating, anti-inflammatory.
Forms a specific and stimulates non-specific immunity.
Pharmacodynamics
The active component - a suspension of bacterial culture - contains inactivated bacteria and their metabolic products. Stimulates the T-system of immunity, increases the phagocytic activity of leukocytes and cells of the reticuloendothelial system, a number of humoral factors of non-specific immunity.
It increases the formation of antibodies at the site of exposure and local tissue resistance to the effects of pathogenic microflora due to the content of concentrated lipopolysaccharides of cell membranes and metabolites of E. coli of various strains, resistant to antibiotics and other antibacterial agents. Reduces exudation, normalizes the permeability and tone of blood vessels, stimulates the regeneration of damaged tissues.
Indications
Hemorrhoids (mainly suppositories), perianal dermatitis (ointment), anal and genital itching, especially resistant to other drugs, anopapillitis, anal fissure (ointment), condition after anorectal surgery (to stimulate wound healing).
Contraindications
Hypersensitivity to phenol.
Side effects
Rarely, allergic reactions (associated with the use of phenol as a preservative).
Interaction
The drug interaction of the drug Posterisan is not described.
How to take, course of administration and dosage
Apply in the morning and evening, as well as after each bowel movement.
Perhaps the combined use of ointments and suppositories.
After stopping the symptoms of the disease, treatment is continued for 2-3 weeks to stabilize the effect and prevent relapse.
Overdose
Currently, cases of an overdose of the drug Posterisan have not been reported.
Special instructions
Phenol is used as a preservative in the preparation.
Release form
rectal candles