Product Overview
Composition
Active substance:
Antibodies to the brain-specific protein S-100 affinely purified - 0.003 g*.
Excipients:
lactose monohydrate 0.267 g,
microcrystalline cellulose 0.03 g,
magnesium stearate 0.003 g.
* apply monohydrate to lactoses in the form of an aqueous-alcohol mixture with a content of no more than 10 -1991 ng/g of the active form of the active substance.
Antibodies to the brain-specific protein S-100 affinely purified - 0.003 g*.
Excipients:
lactose monohydrate 0.267 g,
microcrystalline cellulose 0.03 g,
magnesium stearate 0.003 g.
* apply monohydrate to lactoses in the form of an aqueous-alcohol mixture with a content of no more than 10 -1991 ng/g of the active form of the active substance.
Pharmacological action
The drug modifies the functional activity of the S-100 protein, which performs conjugation of information and metabolic processes in the brain. Sensitizes the neuronal membrane, modulates the synaptic plasticity of neurons. It has a modifying effect on the functional state of brain structures involved in the formation of alcohol dependence: hypothalamus, hippocampus, etc.
In case of alcohol addiction, it has a normalizing effect on the system of positive emotional reinforcement, which leads to a decrease in the frequency of self-stimulation of the lateral hypothalamus. Reduces the paternal activity of hippocampal neurons; reduces the number of circulating immunocomplexes in peripheral blood, which correlates with a decrease in ethanol consumption. Helps to strengthen the braking effects of GABA in the CNS.
It has been experimentally established that the drug restores neurotransmitory balance and conditional reflex activity. Increases brain resistance to hypoxia and toxic effects.
In case of alcohol addiction, it has a normalizing effect on the system of positive emotional reinforcement, which leads to a decrease in the frequency of self-stimulation of the lateral hypothalamus. Reduces the paternal activity of hippocampal neurons; reduces the number of circulating immunocomplexes in peripheral blood, which correlates with a decrease in ethanol consumption. Helps to strengthen the braking effects of GABA in the CNS.
It has been experimentally established that the drug restores neurotransmitory balance and conditional reflex activity. Increases brain resistance to hypoxia and toxic effects.
Indications
Proproten-100 is indicated for use in adults.
It is used for alcohol addiction to reduce alcohol attraction and reduce the likelihood of alcohol recurrence.
Use during pregnancy and breastfeeding
Proproten-100 is contraindicated for use in women during pregnancy and breastfeeding.
Contraindications
Increased individual sensitivity to the components of the drug;
pregnancy and breastfeeding;
age up to 18 years;
lactase deficiency, lactose intolerance, glucose-galactose malabsorption.
Side effects
Individual hypersensitivity reactions to the components of the drug are possible.
Interaction
To date, no cases of incompatibility with other drugs have been identified.
How to take, course of administration and dosage
The risk is not intended to divide the tablet into parts.
For one dose - keep 1 tablet in your mouth until completely dissolved (not during meals).
To prevent recurrence of alcoholism, the drug is taken 2 tablets (1 tablet 2 times a day) for 6 months; after accidental alcohol consumption, take an additional 2 tablets of the drug 2 times - day and night.
For one dose - keep 1 tablet in your mouth until completely dissolved (not during meals).
To prevent recurrence of alcoholism, the drug is taken 2 tablets (1 tablet 2 times a day) for 6 months; after accidental alcohol consumption, take an additional 2 tablets of the drug 2 times - day and night.
Overdose
In case of accidental overdose, dyspepsia phenomena are possible due to the fillers included in the drug.
Special instructions
The drug contains lactose monohydrate, so it is not recommended to be prescribed to patients with congenital galactosemia, malabsorption syndrome of glucose, or congenital lactase deficiency.
Impact on the ability to drive vehicles, mechanisms
During the treatment of alcohol addiction, taking into account the specifics of the disease, you should refrain from driving.
Impact on the ability to drive vehicles, mechanisms
During the treatment of alcohol addiction, taking into account the specifics of the disease, you should refrain from driving.
Release form
Tablets for resorption
Storage conditions
At a temperature not exceeding 25 °C.
Keep out of reach of children.
During the period of use of the drug, store contour cell packaging in a cardboard pack provided by the manufacturer.
Keep out of reach of children.
During the period of use of the drug, store contour cell packaging in a cardboard pack provided by the manufacturer.
Shelf life
3 years. Do not apply after the expiration date.