Riboxin, 200 mg, 50 pcs.

Biosynthesis, Russia

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Product Overview

Composition

1 tab. inosine - 200 mg

pharmachologic effect

Riboxin - a derivative (nucleoside) of purine - a precursor of adenosine diphosphate ATP. Refers to a group of drugs that stimulate metabolic processes.

It has antihypoxic and antiarrhythmic effects. Increases the energy balance of the myocardium, improves coronary circulation, prevents the consequences of intraoperative renal ischemia. It takes a direct part in the metabolism of glucose and promotes the activation of metabolism in conditions of hypoxia and in the absence of ATP.

It activates the metabolism of pyruvic acid to ensure the normal process of tissue respiration, and also promotes the activation of xanthine dehydrogenase.

Stimulates the synthesis of nucleotides, enhances the activity of certain enzymes of the Krebs cycle. Penetrating into cells, it has a positive effect on metabolic processes in the myocardium - it increases the strength of heart contractions and promotes more complete relaxation of the myocardium in diastole, resulting in an increase in stroke volume.

The mechanism of antiarrhythmic action is not fully understood.

Reduces platelet aggregation, activates tissue regeneration (especially myocardium and gastrointestinal mucosa).

 

Indications

Complex treatment of myocardial infarction, ischemic heart disease, cardiac arrhythmias caused by the use of cardiac glycosides, against the background of myocardial dystrophy after infectious diseases.
 
Liver diseases (hepatitis, cirrhosis, fatty degeneration).
 
Surgery on an isolated kidney (as a means of pharmacological protection when the blood circulation is turned off).

Contraindications

Hypersensitivity to the drug, gout, hyperuricemia, pregnancy, lactation, age up to 18 years (efficacy and safety have not been established). Use with caution in case of renal failure.

Side effects

Allergic reactions: itching, flushing of the skin (the drug should be canceled). Rarely: an increase in the concentration of uric acid in the blood, exacerbation of gout (with prolonged use).

Interaction

When used as part of complex therapy, Riboxin increases the effectiveness of antiarrhythmic, antianginal and inotropic drugs.
 
Clinically significant interaction of Riboxin with drugs from other groups has not been described.

How to take, course of administration and dosage

Inside, before meals. First, appoint 0.2 g 3-4 times a day, then within 2-3 days the dose is increased to 9.4 g 3-6 times a day. The course is 1–3 months.

Special instructions

Riboxin is not used for emergency correction of cardiac dysfunction.

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