Selank nasal drops 0.15%, 3 ml

Pharmacotherapeutic group:

anxiolytic agent (tranquilizer).

ATX code: N05BX

pharmachologic effect

Pharmacodynamics

Selank® is a synthesized analogue of endogenous peptide taftcin, has an original mechanism of neurospecific action on the central nervous system.

Selank® has an anti-anxiety effect with an antidepressant effect; antiasthenic action.

Relieves symptoms of anxiety, anxiety, fear, apathy, depression and asthenia.

It has a positive effect on cognitive functions, improves memory, speech, increases attention, activates learning processes, in particular, memorization, analysis and reproduction of information. Normalizes psychomotor reactions.

When stressed, Selank® eliminates negative emotional stress and stimulates the development of adaptive behavior aimed at achieving a beneficial result.

Pharmacokinetics

Selank® is administered intranasally (nasal drops). The absolute bioavailability of Selank® when administered to the nasal mucosa is 92.8%. The drug is rapidly absorbed from the nasal mucosa and after 30 seconds is found in the blood plasma, and then quickly distributed to various organs and tissues. Penetrates into the brain tissue. Plasma concentration decreases progressively within 5-5.5 minutes. In daily urine, neither unchanged drug nor metabolites are detected, which is due to the rapid degradation of Selank® under the influence of tissue peptidases.

Anxiety states:

• unmotivated anxiety, worry;

• panic attacks;

• neurasthenia;

• asthenia;

• instability of mood;

• sleep disorders;

• decreased will, initiation of activity, indecision, difficulty in making decisions, self-doubt;

• lack of confidence in communication;

• adjustment disorder;

Prevention and Treatment of Stress Disorders.

Contraindicated during pregnancy and lactation.

Individual intolerance to the drug.

Pregnancy, breastfeeding period (efficacy and safety studies have not been conducted).

Children under 18 years of age (efficacy and safety studies have not been conducted).

With increased sensitivity to the perception of smell and taste, when the drug gets from the nasal cavity to the mucous membrane of the pharynx, unpleasant taste sensations may appear. Development of allergic reactions with individual intolerance is possible.

If any of the side effects indicated in the instructions are aggravated, or you notice any other side effects not listed in the instructions, inform your doctor.

Selank® does not affect the effects of drugs that depress and stimulate the central nervous system - haloperidol, pentobarbital, hexobarbital, analeptics.

Selank® can be combined with any psychoactive and neuroactive therapy.

Selank® is safe when used together with ethanol-containing products.

If you are taking other medicines (including over-the-counter medicines), consult your doctor before using Selank®.

Selank® is administered intranasally using a bottle sealed with a plastic screw cap or dropper cap.

If the vial is sealed with a plastic screw cap, upon initial use, remove the plastic screw cap and replace it with the supplied pipette with cap.

Draw up the drug into a pipette.

Squeeze the required number of drops of the drug onto the clean mucous membrane of the nasal passage, then pinch the nostril with your finger for a short time.

If the bottle is sealed with a dropper cap, carefully cut off the tip of the pipette, tightly close the pipette cap. Invert the bottle before use so that the liquid fills the entire space of the pipette. Remove the cap. Squeeze the required number of drops of the drug onto the clean mucous membrane of the nasal passage, then pinch the nostril with your finger for a short time.

The instillation of the drug into the nasal passages is carried out in a sitting position with the head slightly thrown or tilted to one side, after which each nostril is clamped with a finger for a short time.

The effectiveness of absorption may be reduced in the presence of increased secretions of the nasal mucosa, therefore, it is recommended to clear the nasal passage before use (instillation).

Dose: 2 drops in each nasal passage 3 times a day.

The duration of the course of the drug is 14 days. If necessary, the course of treatment can be repeated in 1-3 weeks, after consulting a doctor.

Use the drug only according to the method of administration and in the doses indicated in the instructions. If necessary, please consult your doctor before using this medication.

Influence on the ability to drive vehicles and other mechanisms that require increased concentration

The absence of hypnosedative and muscle relaxant properties of the drug and the presence of a positive effect on cognitive functions make it possible to use Selank in people of various professions, including those requiring increased attention and coordination of movements (vehicle drivers, operators).

Nasal drops

Store in a dark place at a temperature not exceeding 10 C.

Do not freeze. Store the opened bottle at a temperature not exceeding 25 C for no more than 15 days.

Keep out of the reach of children.