Tanakan, 40 mg

Active substance: 

dry standardized Ginkgo biloba extract (EGb 761) 40 mg in 1 tablet, including heterosides 24% ginkgolid bilobalides 6%.

Excipients: 

lactose monohydrate, 

microcrystalline cellulose, 

corn starch, 

silica colloidal 

talc, 

magnesium stearate.

Shell composition: 

hypromellose, 

macrogol 400, 

macrogol 6000, 

titanium dioxide 

iron dioxide red.

The basis of its action is the effect on metabolic processes in cells, vasomotor reactions of blood vessels and rheological properties of blood. Tanakan contributes to the enrichment of the brain with oxygen and glucose, normalizes microcirculation, tone of arteries and veins. In addition, it improves blood flow, inhibits platelet activation factor, and prevents the aggregation of red blood cells. 

The drug also normalizes metabolism, prevents the formation of free radicals and lipid peroxidation of cell membranes, has an antihypoxic effect on tissues. The drug affects the release, catabolism and reuptake of neurotransmitters, as well as the ability to bind to membrane receptors. 

The bioavailability of ginkgolides and bilobalides is 80-90%. The maximum concentration is reached after about 1-2 hours. The elimination half-life is 4-10 hours. The active substance does not break down and is almost completely excreted in the urine. A small amount - with feces.

• treatment of cognitive impairment for older people (except for dementia, vascular disorders, Parkinson's disease, metabolic disorders);
• symptomatic treatment of tinnitus;
• vertigo therapy; 
• intermittent claudication in the case of chronic obliterating arteriopathies of the lower extremities; 
• dizziness and coordination disorders of vascular origin; Raynaud’s disease and syndrome.

• erosive gastritis in the acute phase;
• peptic ulcer of the stomach and duodenum in the acute phase;
• acute cerebrovascular accident;
• acute myocardial infarction;
• decreased blood coagulability;
• congenital galactosemia, lactase deficiency, lactose intolerance, glucose / galactose malabsorption syndrome (for tablets);
• children and adolescents under 18 years
• pregnancy;
• lactation (breastfeeding);
• hypersensitivity to any of the components of the drug.

On the part of the blood coagulation system: a decrease in blood coagulability and the possibility of bleeding (with prolonged use). Dermatological reactions: eczema.

From the side of the central nervous system: headache, dizziness, tinnitus. 

From the digestive system: nausea, vomiting, abdominal pain, dyspepsia, diarrhea. In case of adverse reactions, the patient should stop taking the drug and consult a doctor.

Interaction with drugs metabolized with the participation of the CYP3A4 isoenzyme and having a low therapeutic index should be avoided with caution. 

You can not use Tanakan in combination with drugs, including acetylsalicylic acid, drugs that reduce blood coagulation, and anticoagulants. 

The combination with cephalosporin group antibiotics, chloramphenicol, thiazide diuretics, oral hypoglycemic agents, 5-nitroimidazole derivatives, cytostatics, tranquilizers, Gentamicin, Disulfiram, anticonvulsants, antifungal drugs, Ketoconazole, hypertrophy, triple,

Assign 40 mg (1 tablet or 1 ml of oral solution) 3 times / day with meals.

Take inside.

The tablet should be washed down with half a glass of water.

Since Tanakan® in the form of tablets contains lactose, it should not be prescribed to patients with congenital galactosemia, glucose or galactose malabsorption syndrome, or with lactase deficiency.