Product Overview
Structure
active substance:
thymogen (glutamyl tryptophan) 100 mcg;
Excipients:
sodium chloride,
water for injections
pharmachologic effect
Timogen is an immunostimulating agent, a dipeptide.
It has immunomodulatory, anti-inflammatory, desensitizing, antioxidant, reparative effects. It interacts with T-lymphocytes, Langerhans cells (macrophages) and mast skin cells, contributing to the normalization of their functional activity and intercellular interactions.
Helps reduce antigen / IgE-mediated production of inflammatory mediators of the level of pro-inflammatory cytokines and biogenic amines (histamine and serotonin) in the skin cells. Causes a decrease in skin manifestations of allergic reactions with increased sensitivity to various allergens. Suppresses the inflammatory response in response to exposure to skin irritants in contact dermatitis. Reduces skin inflammation and itching of allergic dermatitis in the acute phase of the disease.
It inhibits the processes of free radical oxidation in pathologically altered skin cells, preventing their damage and death, and stimulates the production of antioxidant cell defense factors.
Stimulates the proliferation of keratinocytes, fibroblasts and endothelial cells, contributing to the regeneration of damaged skin. It accelerates wound healing, stimulates cellular and humoral (tissue) defense factors.
Systemic effects are mild due to limited absorption through the skin.
Indications
- Combined therapy of acute and chronic infectious and inflammatory diseases accompanied by a decrease in cellular immunity.
- Prevention of infectious complications, immune suppression, blood formation, regeneration processes in the post-traumatic and postoperative period, during radiation therapy or chemotherapy, using massive doses of antibiotics.
- Prevention and complex therapy of viral and bacterial infections, acute and chronic respiratory diseases.
Contraindications
Individual intolerance to the drug, pregnancy, breastfeeding.
Side effects
Allergic reactions.
Interaction
Increases the effectiveness of other types of therapy (cytostatics, radiation therapy, etc.);
It is not recommended to use simultaneously with large doses of glucocorticosteroid drugs.
How to take, course of administration and dosage
The solution is administered intramuscularly once a day for adults at 100 mcg (300 - 1000 mcg per course);
children under 1 year old - 10 micrograms, from 1 year to 3 years old - 10-20 micrograms, from 4 to 6 years old - 20-30 micrograms, from 7 to 14 years old - 50 micrograms.
The duration of the course of treatment is 3-10 days, depending on the severity of immunity disorders.
A second course of treatment is possible after 1-6 months.
Release form
Intramuscular solution