Product Overview
Composition
Active substance:
thioctic acid (alpha lipoic acid).
Excipients:
calcium stearate
potato starch,
colloidal silicon dioxide (aerosil),
croscarmellose sodium (primellose),
lactose (milk sugar),
Castor oil,
povidone (collidone 30),
microcrystalline cellulose.
pharmachologic effect
Pharmacological action - neurotrophic, metabolic, antioxidant.
Indications
- Alcoholic polyneuropathy.
- Diabetic polyneuropathy.
Contraindications
- Children under 18 years of age (efficacy and safety of use not established).
- Hypersensitivity to the components of the drug.
- Pregnancy, the period of breastfeeding (there is no sufficient experience with the use of the drug).
- Lactose intolerance, lactase deficiency, glucose-galactose malabsorption.
Side effects
Tielepta® is generally well tolerated.
Possible dyspepsia, including nausea, vomiting, heartburn. In some cases, the development of skin allergic reactions (urticaria) is possible.
Hypoglycemia may develop (due to improved glucose uptake).
Interaction
With the simultaneous administration of thioctic acid and cisplatin, a decrease in the effectiveness of cisplatin is noted.
Thioctic acid binds metals, so it should not be prescribed simultaneously with drugs containing metals (for example, iron, magnesium, calcium) - the interval between doses should be at least 2 hours.
When thioctic acid and insulin or oral hypoglycemic drugs are used, their effect may be amplified.
Ethanol and its metabolites weaken the effect of thioctic acid.
How to take, course of administration and dosage
Inside.
Prescribe 600 mg 1 time per day.
The tablets are taken on an empty stomach, approximately 30 minutes before the first meal, without chewing and drinking a small amount of liquid.
The duration of treatment is determined by the doctor.
Special instructions
Patients taking the drug Tieolepta® should refrain from drinking alcohol.
In patients with diabetes, constant monitoring of blood glucose concentration is necessary, especially at the initial stage of therapy.
In some cases, it is necessary to reduce the dose of insulin or an oral hypoglycemic drug in order to avoid the development of hypoglycemia.
Release form
Pills.
