Product Overview
Solution for intramuscular and subcutaneous administration
Composition Unitiol
1 ml of a 5% solution for intramuscular and subcutaneous administration contains: unitiol 0.05 g.
Excipients: disodium salt of ethylenediaminetetraacetic acid (Trilon B), sulfuric acid 0.1 M and water for injection.
Unitiol Packaging
10 ampoules of 5 ml.
Pharmacological action Unitiol
Unitiol is a complexing agent that has a detoxifying effect. The active sulfihydryl groups of unitiol, interacting with thiol poisons (arsenic compounds, salts of heavy metals) and forming non-toxic, water-soluble compounds with them, restore the functions of the enzyme systems of the body affected by poison. In diabetic polyneuropathy, it reduces pain, improves the condition of the peripheral nervous system and normalizes capillary permeability.
Indications Unithiol
- Intoxication: arsenic, mercury, bismuth, chromium, cardiac glycosides.
- Hepatocerebral dystrophy (Wilson-Konovalov disease).
- Diabetic polyneuropathy.
- Chronic alcoholism (as part of complex therapy).
- Delirious psychosis.
Contraindications Unitiol
- Hypersensitivity to the drug.
- Liver failure.
- Arterial hypertension.
Dosage and administration Unitiol
Intramuscularly, subcutaneously.
With arsenic intoxication - 5-10 ml of the drug (based on 0.005 g / 1 kg), 3-4 times on the first day, 2-3 times on the second day, 1-2 times on the following days.
In case of poisoning with mercury compounds - according to the same scheme for 6-7 days. Treatment is carried out until the signs of intoxication disappear.
With digitalis intoxication, in the first 2 days, 5-10 ml of a 5% aqueous solution is administered 3-4 times a day, then 1-2 times a day until the cardiotoxic effect ceases.
With hepatocerebral dystrophy - i / m 5-10 ml of 5% solution daily or every other day; course of treatment - 25-30 injections; if necessary, repeat after 3-4 months.
In chronic alcoholism, 3-5 ml is prescribed 2-3 times a week.
For stopping delirium - once 4-5 ml of solution.
Side effects of Unithiol
Nausea, dizziness, tachycardia, pallor of the skin; allergic reactions are possible.
Drug Interactions Unitiol
The simultaneous use of unitiol with drugs that include heavy metals and alkalis is not recommended, because unitiol is rapidly decomposed.
Overdose of Unithiol
In recommended doses and according to the indications of the phenomena of overdose does not occur.
Storage conditions Unitiol
Store in a dark place at a temperature of 0 to 25 ° C.
