Product Overview
Composition
100 g drops for oral administration contain:
phenobarbital 2 g,
ethyl bromisovalerianate (ethyl ester of α-bromisovalerianic acid) 2 g,
excipients:
peppermint oil - 0.14 g;
Spanish hop oil (oregano oil) - 0.02 g;
ethanol (ethyl alcohol) 95% - 52.8 g;
purified water - 43.04 g.
pharmachologic effect
Valoserdin is a combined drug whose therapeutic effect is due to the pharmacological properties of the components that make up its composition. It has a sedative and antispasmodic effect.
Phenobarbital has sedative and mild hypnotic effects. Helps reduce central nervous system excitation and facilitates the onset of natural sleep, enhancing the sedative effect of other components.
Ethyl bromisovalerianate also has a sedative (like valerian effect) and antispasmodic effect.
Indications
- vegetative-vascular dystonia
- increased irritability
- insomnia
- arterial hypertension (early stages).
Contraindications
- hypersensitivity to the components of the drug;
- severe renal and / or liver dysfunction;
- porphyria;
- pregnancy;
- period of breastfeeding;
- age to 18 years.
Due to the absolute ethanol content of more than 3 g in a daily dose, Valoserdin is contraindicated in patients with liver diseases, alcoholism, traumatic brain injury and brain diseases.
Side effects
Valoserdin, as a rule, is well tolerated even with prolonged use. In some cases, drowsiness and slight dizziness may occur during the day. With prolonged use of large doses, chronic bromine poisoning may develop, characterized by the following manifestations: depressive mood, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired coordination of movements.
If you experience any side (unusual) effects that are not reflected in the description, you must inform your doctor.
Interaction
The simultaneous use with antipsychotics and tranquilizers enhances, and with CNS stimulants, weakens the effect of each of the components of the drug.
Alcohol enhances the effects of Valoserdine and may increase its toxicity.
The presence of phenobarbital in the composition can induce liver enzymes, and this makes it undesirable to use it simultaneously with drugs that are metabolized in the liver, because their concentration, and therefore effectiveness, will decrease as a result of a more accelerated metabolism (indirect anticoagulants, antibiotics, sulfonamides).
Phenobarbital weakens the effect of coumarin derivatives, corticosteroids, griseofulvin, and oral contraceptives.
How to take, course of administration and dosage
Inside, before eating, previously dissolved in a small amount (30-50 ml) of water. Adults are usually prescribed 15–20 drops 3 times a day. With tachycardia, a single dose may be increased to 40-50 drops.
The duration of the drug is determined individually by the doctor.
Overdose
Symptoms: with mild to moderate intoxication, drowsiness, dizziness, psychomotor disturbances are observed. In severe cases - coma, decreased blood pressure, respiratory failure, tachycardia, vascular collapse, decreased peripheral reflexes.
Treatment: gastric lavage, the appointment of activated carbon. Call a doctor.
Special instructions
Before using the drug, you should consult your doctor.
If necessary, the appointment of the drug during breastfeeding should decide on the termination of breastfeeding.
With prolonged use of the drug, the formation of drug dependence is possible; accumulation of bromine in the body and the development of poisoning by it is possible.
The drug contains at least 52 vol.% Ethanol.
The maximum single dose of the drug contains 1.03 g of absolute ethanol; the maximum daily dose is 3.09 g of absolute ethanol.
Influence on the ability to drive vehicles, mechanisms. When using the drug, it is not recommended to perform potentially hazardous activities that require an increased concentration of attention and speed of psychomotor reactions (including driving vehicles, working with moving mechanisms).
Release form
A clear, colorless liquid with a specific aromatic odor.
